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There are 2 primary mechanisms: Ascorbic Acid (Ascorbate) uptake using sodium-dependent vitamin C transporter (SVCT) 1 or 2 Ascorbic Acid (Ascorbate) Recycling Ascorbic Acid (Ascorbate) transport using sodium-dependent vitamin C transporter (SVCT) 1 or 2 As shown below, SVCT 1 and SVCT 2 transport ascorbic acid or ascorbate into the cell against the concentration gradient (represented by the orange wedge in the figure below)

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10.1161/STROKEAHA.115.011932 [DOI] [PMC free article] [PubMed] [Google Scholar] Hossain, M